Please be patient! It may take up to ONE minute to load all the Engines.
Problems? Please contact our support.
Alternative namesAmino acids - urine; Urine amino acids
DefinitionThis test screens for increased levels of amino acid excretion in the urine that indicates possible inborn errors of metabolism caused by a specific enzyme deficiency.
How the test is performed
To obtain a clean-catch urine sample, males should wipe clean the head of the penis and females need to wipe between the labia with soapy water and rinse well. Sometimes a special clean-catch kit is provided with cleansing solution and sterile wipes.
After urinating a small amount into the toilet bowl to clear the urethra of contaminants, collect a sample of urine in a clean or sterile container. About 1 to 2 ounces of urine is needed for a test. Remove the container from the urine stream without stopping the flow. You may finish voiding into the toilet bowl. Take the sample to the lab.
How to prepare for the testNo restriction of food or fluid is necessary.
Inform your health care provider of any medication you or your child has used recently. If your infant is breast feeding and having this test performed, inform the health care provider of any medications the mother is taking.
How the test will feelThe test involves only normal urination.
Why the test is performed
This test is performed to assess amino acid levels in the urine. It is common for some of each amino acid to be in the urine, but elevated levels of individual amino acids indicates a possible inborn enzyme deficiency.
While this test shows increased levels of amino acids in the urine, a 24-hour quantitative urine chromatography is necessary to accurately measure the elevated levels of the specific amino acids.
The increased levels also show up in the blood plasma (see plasma amino acids ). If the test is performed early enough on infants and the defect is treated, the severe mental retardation that can result may be prevented.
Note: all measurements in micro mole per deciliter (micro mol/dl)
What abnormal results meanIncreased total urine amino acids may indicate any of the following:
What the risks areIn infants, the collection device should be removed carefully to prevent irritation.
Special considerationsFailure to have the urine sample promptly evaluated in the laboratory alters the results of the test. This test is ineffective in a neonate (the first six weeks after birth) who has not ingested dietary protein in the last 48 hours.
Update Date: 9/3/2003Michael C. Milone, M.D., Ph.D., Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT