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Phenindamine overdose


Alternative names

This poisoning is from an overdose of phenindamine.

Poisonous Ingredient

Phenindamine

Where Found

  • Nolahist
  • Amilon
  • Fenaclor
  • Nolamine
  • Norphenamine
  • Prophamine

Symptoms

  • Body as a whole
    • Unsteadiness
    • Tremor
    • Convulsions
    • Fever
    • Flushed skin
  • Eyes, ears, nose, and throat
    • Dilated pupils
  • Heart and blood vessels
    • Rapid heartbeat
  • Nervous system
    • Depression
    • Excitation
    • Drowsiness
    • Nervousness
    • Hallucinations
    • Disorientation
    • Delirium

Home Treatment

Seek medical care immediately. Call Poison Control. Do not induce vomiting.

Before Calling Emergency

Determine the following information:
  • The patient's age, weight, and condition
  • Name of product (as well as the ingredients and strength, if known)
  • The time it was swallowed
  • The amount swallowed
  • If the medication was prescribed for the patient

Poison Control, or a local emergency number

See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room

Some or all of the following procedures may be performed:
  • For swallowed poison
    • Placement of a tube down the nose and into the stomach (a nasogastric tube, or an NG tube) to wash out the stomach (gastric lavage)
    • Activated charcoal administration
    • Endoscopy -- the placement of a camera down the throat to see the extent of burns to the esophagus and the stomach
    • Give IV fluids
    • Admission to the hospital
    • Give an antidote
    • Treat the symptoms
  • For inhaled poisons
    • A breathing tube may need to be inserted
    • Oxygen
    • Admission to the hospital or to the intensive care unit
    • Bronchoscopy (inserting a camera down the throat into the airway to evaluate the extent of burns to the airway and lungs)
  • For skin exposure
    • Irrigation (washing of the skin), perhaps every few hours for several days
    • Skin debridement (surgical removal of burned skin)
    • Admission or transfer to a hospital that specializes in burn care

Expectations (prognosis)

If the patient survives the first 24 hours, survival is likely. Few patients actually die from an antihistamine overdose.

Update Date: 1/29/2004

Cherlin Johnson, M.D., Department of Emergency Medicine, University of Southern California, Los Angeles, CA. Review provided by VeriMed Healthcare Network.

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT
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