Please be patient! It may take up to ONE minute to load all the Engines.
Problems? Please contact our support.
Alternative namesPrimary hypogonadism - male
DefinitionTesticular failure is the inability of the testicles to produce sperm or male hormones.
Causes, incidence, and risk factors
Causes of testicular failure include chromosomal abnormalities, testicular torsion , direct trauma to the testicles, diseases that affect the testicle (such as mumps , orchitis [inflammation of the testes], and testicular cancer ), and a variety of drugs. The condition is uncommon.
Increased risk is associated with activities that may cause constant, low-level trauma to the scrotum (such as riding a motorcycle) or frequent administration of a drug known to affect testicular function (such as heavy marijuana use or taking some prescription medications). Men who had undescended testicles at birth are at higher risk.
Signs and testsA physical examination may reveal:
TreatmentSupplementation of male hormones may be successful in treating some forms of testicular failure. In cases that appear to be related to specific exposure or activity exposure, removal of the drug or activity may result in return of normal testicular function.
Expectations (prognosis)Many forms of testicular failure are irreversible. However, androgen replacement is effective in reversing symptoms, though it may not restore fertility.
ComplicationsTesticular failure prior to the onset of puberty will prohibit normal growth, specifically the development of adult male characteristics.
Calling your health care providerCall for an appointment with your health care provider if symptoms occur.
PreventionAvoid higher-risk activities or monitor testicular function when involved in such activities. Also, cease the activity with the initial onset of symptoms.
Update Date: 10/6/2003Tarun Jain, M.D., Endocrinology & Infertility Division, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network
Last updated: Tue, 06 Jan 2009 00:20:03 GMT