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Lack of intrinsic factor

Alternative names

Intrinsic factor - lack of


Intrinsic factor is a natural substance normally present in the stomach. It is essential to the digestion of vitamin B-12 . Lack of intrinsic factor leads to pernicious anemia and vitamin B-12 deficiency.

Babies that are born without intrinsic factor cannot properly absorb vitamin B-12 starting around 6 months of age, while the juvenile type tends to manifest itself at an age greater than 10 years.

Update Date: 6/2/2003

Scott Howard, M.D., M.S., Department of Pediatric Hematology/Oncology, St. Jude Children’s Research Hospital, Memphis, TN. Review provided by VeriMed Healthcare Network.

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT