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Digoxin - test


A test that measures the concentration of digoxin in blood.

How the test is performed

Adult or child:
Blood is drawn from a vein ( venipuncture ), usually from the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and a tourniquet (an elastic band) or blood pressure cuff is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the tourniquet to distend (fill with blood). A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the tourniquet is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding .

Infant or young child:
The area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.

How to prepare for the test

Consult the health care provider about the need to take (or not take) usual medications before the test.

Infants and children:
The physical and psychological preparation you can provide for this or any test or procedure depends on your child's age, interests, previous experiences, and level of trust. For specific information regarding how you can prepare your child, see the following topics as they correspond to your child's age:
  • infant test or procedure preparation (birth to 1 year)
  • toddler test or procedure preparation (1 to 3 years)
  • preschooler test or procedure preparation (3 to 6 years)
  • schoolage test or procedure preparation (6 to 12 years)
  • adolescent test or procedure preparation (12 to 18 years)

How the test will feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed

The main purpose of this test is to monitor patients taking digoxin in order to determine the effective drug dosage and prevent toxicity. Monitoring of drug levels is important in people taking digitalis medications such as digoxin, because the margin of safety between therapeutic levels and toxic levels is narrow.

Normal Values

Normal values range from 0.8 to 2.0 ng/ml.

Note: ng/ml = nanogram per milliliter

What abnormal results mean

  • inadequate or excessive medication dosage
  • digitalis toxicity is present or is likely to develop (elevated value)

What the risks are

  • excessive bleeding
  • fainting or feeling light-headed
  • hematoma (blood accumulating under the skin)
  • infection (a slight risk any time the skin is broken)
  • multiple punctures to locate veins

Special considerations

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Update Date: 5/6/2002

Victoria Kennedy, RN, A.D.A.M. editorial. Previous review: Michael C. Milone, M.D., Ph.D., Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network (2/17/2002).

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT