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Desipramine hydrochloride overdose


Alternative names

Poisoning from an overdose of desipramine, which is a tricyclic antidepressent.

Poisonous Ingredient

  • desipramine

Where Found

  • Norpramin
  • Nebril
  • Nortimil
  • Pertofrane
  • Pertofrin
  • Sertofren

Symptoms

  • body as a whole
    • dry mouth
    • urinary hesitancy
    • convulsions
    • shock
    • incoordination
  • respiratory
    • breathing slowed and labored
  • eyes, ears, nose, and throat
    • blurred vision
  • gastrointestinal
    • vomiting
  • heart and blood vessels
    • irregular heartbeat
    • low blood pressure
  • nervous system
    • drowsiness
    • stupor
    • coma
    • agitation
    • restlessness
    • hallucinations

Home Treatment

Call Poison Control.

Before Calling Emergency

Determine the following information:
  • the patient's age, weight, and condition
  • the name of the product (ingredients and strengths if known)
  • the time it was swallowed
  • the amount swallowed
  • if the medication was prescribed for the patient

Poison Control, or a local emergency number

They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room

Some or all of the following procedures may be performed:
  • Administer activated charcoal.
  • Use gastric lavage .
  • Monitor the patient's vital signs (temperature, pulse , rate of breathing, blood pressure ).
  • Maintain the patient's airway.
  • Institute fluid replacement, if appropriate.
  • Treat the symptoms.

Expectations (prognosis)

The amount swallowed and the time before appropriate therapy is initiated usually determine the final outcome. The sooner therapy is applied, the greater the chance of a positive outcome. This can be an extremely serious overdose

Update Date: 2/12/2004

Cherlin Johnson, M.D., Department of Emergency Medicine, University of Southern California, Los Angeles, CA. Review provided by VeriMed Healthcare Network.

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT
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