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Pheniramine overdose

Alternative names

This poisoning is from an overdose of pheniramine.

Poisonous Ingredient


Where Found

  • Ru-Tuss with Hydrocodone
  • Citra Forte
  • Dehistine D
  • Liqui-Histine
  • Poly-D
  • Poly-Histine

Note: This list may not be all inclusive.


  • Body as a whole
    • Unsteadiness
    • Tremor
    • Convulsions
    • Fever
    • Flushed skin
  • Eyes, ears, nose, and throat
    • Dilated pupils
  • Heart and blood vessels
    • Rapid heartbeat
  • Nervous system
    • Depression
    • Excitation
    • Drowsiness
    • Nervousness
    • Hallucinations
    • Disorientation
    • Delirium

Home Treatment

Seek medical care immediately. Call Poison Control. Do not induce vomiting.

Before Calling Emergency

Determine the following information:
  • The patient's age, weight, and condition
  • Name of product (as well as the ingredients and strength, if known)
  • The time it was swallowed
  • The amount swallowed
  • If the medication was prescribed for the patient

Poison Control, or a local emergency number

See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room

  • For swallowed poison
    • Placement of a tube down the nose and into the stomach (a nasogastric tube, or an NG tube) to wash out the stomach (gastric lavage)
    • Activated charcoal administration
    • Endoscopy -- the placement of a camera down the throat to see the extent of burns to the esophagus and the stomach
    • Give IV fluids
    • Admission to the hospital
    • Give an antidote
    • Treat the symptoms
  • For inhaled poisons
    • A breathing tube may need to be inserted
    • Oxygen
    • Admission to the hospital or to the intensive care unit
    • Bronchoscopy (inserting a camera down the throat into the airway to evaluate the extent of burns to the airway and lungs)
  • For skin exposure
    • Irrigation (washing of the skin), perhaps every few hours for several days
    • Skin debridement (surgical removal of burned skin)
    • Admission or transfer to a hospital that specializes in burn care

Expectations (prognosis)

If the patient survives the first 24 hours, survival is likely. Few patients actually die from an antihistamine overdose.

Update Date: 1/29/2004

Cherlin Johnson, M.D., Department of Emergency Medicine, University of Southern California, Los Angeles, CA. Review provided by VeriMed Healthcare Network.

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT