Please be patient! It may take up to ONE minute to load all the Engines.
Problems? Please contact our support.
Alternative namesArkless-Graham; Acrodysplasia; Maroteaux-Malamut
DefinitionAcrodysostosis is a congenital (present at birth) deformity of the bones and skeleton, which is usually associated with mental retardation.
Causes, incidence, and risk factors
Acrodysostosis is an inherited disease, but the specific gene is unknown at this time. It is inherited in a dominant fashion, which means that if one parent passes on the defective gene, the child will be affected. The disorder tends to occur with older parental age and affects children of both sexes.
Signs and tests
An examination of the infant confirms the symptoms and signs of this disorder:
There is no treatment or cure for this syndrome. The child should be followed by a medical professional, and referral to a geneticist (specialist in inherited diseases) should be recommended.
Additional resources are available from Little People of America. Call 888-572-2001.
Problems are relative to the degree of skeletal involvement and mental retardation . In general, patients do relatively well.
Calling your health care provider
Call your health care provider if your child seems to be growing or developing slowly or abnormally, or if you notice physical abnormalities in your infant.
Genetic counseling is recommended for people with a family history of this disease who are planning a pregnancy.
Update Date: 1/30/2003Douglas R. Stewart, M.D., Division of Medical Genetics, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT