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Alternative namesPapular acrodermatitis of childhood; Gianotti-Crosti syndrome; Acrodermatitis - infantile lichenoid; Acrodermatitis - papular infantile; Papulovesicular acro-located syndrome
DefinitionAcrodermatitis is a skin condition peculiar to children that may be accompanied by mild symptoms of fever and malaise . It may also be associated with Hepatitis B and other viral infections.
Causes, incidence, and risk factors
The mechanism that causes acrodermatitis is poorly understood, but its association with other infections is well documented. The lesions of acrodermatitis appear as small coppery-red, flat-topped firm papules that appear in crops and sometimes in long linear strings.
The lesions are often symmetric (equal on both sides) and appear on the face, arms and legs, and buttocks. This is one of the few rashes that may also appear on the palms and soles. Generalized enlargement of the lymph nodes and liver may be seen.
In Italian children, acrodermatitis is seen frequently in conjunction with Hepatitis B , but this association is rarely seen in the USA. In addition to Hepatitis B, acrodermatitis has also been associated with Epstein-Barr virus infections (EBV, mononucleosis), cytomegalovirus, coxsackie viruses, parainfluenza virus, respiratory syncytial virus (RSV), and some live virus vaccines.
Other symptoms that may appear include:
Signs and tests
Physical examination confirms the appearance of the rash. The liver and spleen may be enlarged ( hepatosplenomegaly ). The lymph nodes may be enlarged or tender ( lymphadenopathy ).
Tests that may be performed to confirm the diagnosis and to diagnose associated diseases include:
Acrodermatitis by itself is not treated. Associated conditions, such as Hepatitis B and Epstein-Barr virus infection, should be managed appropriately.
Acrodermatitis is considered a self-limiting disease that disappears without complication. However, the associated conditions must be watched carefully.
Complications occur as a result of associated conditions, rather than as a result of acrodermatitis.
Calling your health care provider
Call your health care provider if signs or symptoms (as described here) are present.
Update Date: 10/27/2003Jeffrey Drayer, M.D., Dermatologist, Los Angeles, CA. Review provided by VeriMed Healthcare Network.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT