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In the U.S.-
Pioglitazone (pye-oh-GLI-ta-zone) is used to treat a certain type of diabetes mellitus (sugar diabetes) called type 2 diabetes. It may be used alone, with insulin, or with metformin or another type of oral diabetes medicine called a sulfonylurea.Pioglitazone is to be used when diet and exercise plus another diabetes medicine do not result in good blood sugar control.
This medicine is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pioglitazone, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to pioglitazone. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Pioglitazone has not been studied in pregnant women. However, it is easier during pregnancy to control your blood sugar by using injections of insulin, rather than by taking pioglitazone. Close control of your blood sugar can reduce the chance of your baby gaining too much weight, having birth defects, or having high blood sugar before birth. Pioglitazone should be used during pregnancy only if the potential benefit outweighs the potential risk. Be sure to tell your doctor if you plan to become pregnant or you think you are pregnant.
Breast-feeding- It is not known whether pioglitazone passes into the breast milk of humans. However, pioglitazone is not recommended during breast-feeding.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of pioglitazone in children with use in other age groups.
Older adults- This medicine has been tested in a limited number of patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking pioglitazone, it is especially important that your health care professional know if you are taking the following:
Other medical problems- The presence of other medical problems may affect the use of pioglitazone. Make sure you tell your doctor if you have any other medical problems, especially
Proper Use of This Medicine
Follow carefully the special meal plan your doctor gave you . This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.
Pioglitazone may be taken with or without food.
Certain women may be at an increased risk for pregnancy while taking pioglitazone. Adequate contraception is recommended.
The dose of pioglitazone will be different for different patients. Follow your doctor's orders or the directions on the label . If your dose is different, do not change it unless your doctor tells you to do so.
If you miss a dose of this medicine, take it as soon as you remember. However, if you do not remember it until it is time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
If you experience abdominal or stomach pain, dark urine, loss of appetite, nausea or vomiting, unusual tiredness or weakness, or yellow eyes or skin, check with your doctor immediately . These may be symptoms of liver problems.
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects
It is very important to follow carefully any instructions from your health care team about
Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your antidiabetic medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual.
Symptoms of high blood sugar include blurred vision; drowsiness; dry mouth; flushed, dry skin; fruit-like breath odor; increased urination (frequency and amount); ketones in urine; loss of appetite; stomachache, nausea, or vomiting; tiredness; troubled breathing (rapid and deep); unconsciousness; or unusual thirst.
If symptoms of high blood sugar occur, check your blood sugar level and then call your doctor for instructions .
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT