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Candesartan and Hydrochlorothiazide (Systemic)
In the U.S.-
Candesartan belongs to the class of medicines called angiotensin II receptor antagonists. Hydrochlorothiazide belongs to a class of medicines called thiazide diuretics. When these two medicines are combined, they are used to treat high blood pressure (hypertension).
This medicine is available only with your doctor's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For the combinations of candesartan and hydrochlorothiazide, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to candesartan, hydrochlorothiazide, or any sulfonamide-type medicines. Also tell your health care provider if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Use of candesartan and hydrochlorothiazide combination during pregnancy, especially during the second and third trimesters (after the first 3 months) can cause adverse effects in the newborn. Therefore, it is important that you check with your doctor immediately if you think that you may have become pregnant. Be sure that you have discussed this with your doctor before taking this medicine.
Breast-feeding- It is not known whether candesartan passes into human breast milk. However, it is distributed into animal milk. Thiazides, including hydrochlorothiazide, are distributed into human breast milk.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of candesartan and hydrochlorothiazide combination in children with use in other age groups.
Older adults- This medicine has been tested in patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking candesartan and hydrochlorothiazide combination, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of candesartan and hydrochlorothiazide combination. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
For patients taking this medicine for high blood pressure :
The dose of candesartan hydrochlorothiazide will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of candesartan and hydrochlorothiazide combination. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking candesartan and hydrochlorothiazide .
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
Check with your doctor immediately if you think that you may be pregnant. Candesartan and hydrochlorothiazide may cause birth defects or other problems in the baby if taken during pregnancy.
Do not take other medicines unless they have been discussed with your doctor. This especially includes potassium supplements or salt substitutes that contain potassium, since they may change your blood potassium levels, or over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood pressure.
Dizziness or light-headedness may occur. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you experience these effects.
Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea and vomiting or diarrhea. These conditions may cause you to lose too much water and lead to low blood pressure.
Dizziness, light-headedness, or fainting also may occur if you exercise or if the weather is hot. Heavy sweating can cause loss of too much water and result in low blood pressure. Use extra care during exercise or hot weather.
Avoid alcoholic beverages until you have discussed their use with your doctor. Alcohol may make the low blood pressure effect worse and/or increase the possibility of dizziness or fainting.
For diabetic patients:
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT