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Butorphanol ( byoo-TOR-fa-nole) is a narcotic analgesic (pain medicine) that is sprayed into the nose. It is used to relieve moderate or severe pain. It is also used to relieve pain that occurs after an operation.
Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
If a narcotic is used for a long time, it may become habit-forming (causing mental or physical dependence). Physical dependence may lead to withdrawal side effects when you stop taking the medicine.
This medicine is available only with your doctor's or dentist's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For butorphanol, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to butorphanol or any other narcotic analgesic. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Nasal butorphanol has not been studied in pregnant women. However, studies in animals have shown that butorphanol causes a decreased pregnancy rate and an increase in stillbirths. Before taking this medicine make sure your doctor knows if you are pregnant or if you may become pregnant.
Too much use of butorphanol during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth.
Breast-feeding- Although butorphanol may pass into the breast milk, it is not expected to cause problems in nursing babies.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of butorphanol in children with use in other age groups.
Older adults- Elderly people are especially sensitive to the effects of butorphanol. This may increase the chance of side effects, especially dizziness, during treatment. Studies in older adults show that butorphanol stays in the body for a longer time than it does in younger adults. Your doctor will consider this when deciding on your dose.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking butorphanol it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of butorphanol. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
You will be given an instruction sheet with your prescription for butorphanol that explains how to use the pump spray unit. If you have any questions about using the unit, ask your health care professional.
The dose of butorphanol will be different for different patients. Follow your doctor's or dentist's orders or the directions on the label . The following information includes only the average doses of butorphanol. If your dose is different, do not change it unless your doctor or dentist tells you to do so.
If your medical doctor or dentist has told you to use this medicine on a regular schedule and you miss a dose, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses .
To store this medicine:
Precautions While Using This Medicine
Butorphanol will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicines, including other narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Do not drink alcoholic beverages, and check with your medical doctor or dentist before taking any of the medicines listed above, while you are using this medicine .
This medicine may cause some people to become drowsy, dizzy, or lightheaded, or to feel a false sense of well-being. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and clearheaded .
Dizziness, lightheadedness, or fainting may occur, especially in the first hour after use or when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem.
Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine.
Butorphanol may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.
If you have been using this medicine regularly for several weeks or more, do not suddenly stop using it without first checking with your doctor . Your doctor may want you to reduce gradually the amount you are using before stopping completely, in order to lessen the chance of withdrawal side effects.
If you think you or someone else may have used an overdose, get emergency help at once . Using an overdose of this medicine or taking alcohol or CNS depressants with this medicine may lead to unconsciousness or death. Signs of overdose include convulsions (seizures), confusion, severe nervousness or restlessness, severe dizziness, severe drowsiness, slow or troubled breathing, and severe weakness.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Get emergency help immediately if any of the following symptoms of overdose occur :
Also, check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time, check with your doctor if you notice any of the following side effects:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT