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Antifibrinolytic Agents (Systemic)
Some commonly used brand names are:
In the U.S.-
Another commonly used name for aminocaproic acid is epsilon-aminocaproic acid.
Antifibrinolytic (an-tee-fye-bri-noh-LIT-ik ) agents are used to treat serious bleeding, especially when the bleeding occurs after dental surgery (particularly in patients with hemophilia) or certain other kinds of surgery. These medicines are also sometimes given before an operation to prevent serious bleeding in patients with medical problems that increase the chance of serious bleeding.
Antifibrinolytic agents may also be used for other conditions as determined by your doctor.
Antifibrinolytic agents are available only with your doctor's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For antifibrinolytic agents, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to aminocaproic acid or tranexamic acid. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Studies on birth defects have not been done in humans. However, these medicines have been given to pregnant women without causing birth defects or other problems.
Studies on effects of aminocaproic acid in pregnancy have not been done in animals. Tranexamic acid has not been shown to cause birth defects or other problems in animal studies.
Breast-feeding- These medicines have not been reported to cause problems in nursing babies. However, small amounts of tranexamic acid pass into the breast milk.
Children- Although there is no specific information comparing use of aminocaproic acid or tranexamic acid in children with use in other age groups, these medicines are not expected to cause different side effects or problems in children than they do in adults.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other medical problems- The presence of other medical problems may affect the use of antifibrinolytic agents. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Take this medicine only as directed by your doctor . Do not take more or less of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.
The dose of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
To store this medicine:
Precautions While Using This Medicine
If you will be taking tranexamic acid for longer than several days, your doctor may want you to have your eyes checked regularly by an ophthalmologist (eye doctor). This will allow your doctor to check for unwanted effects that may be caused by this medicine.
If you are using aminocaproic acid syrup as a mouth rinse to control oral bleeding, and you are in the first or second trimester of pregnancy, you should spit out the syrup after rinsing without swallowing it.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
The same effect that makes aminocaproic acid or tranexamic acid help prevent or stop bleeding also may cause blood clots that could be dangerous. Check with your doctor immediately if any of the following possible signs and symptoms of blood clots occur:
Also, check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT