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In the U.S.-
Topiramate (toe-PYRE-a-mate) is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to help control seizures for as long as you continue to take it.
This medicine is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of taking topiramate must be weighed against the good it will do. This is a decision you and your doctor will make. For topiramate, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to topiramate. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Topiramate has not been studied in pregnant women. However, studies in pregnant animals have shown that topiramate may cause birth defects in the offspring, as well as adverse effects in the mother, when given in doses many times higher than the human dose. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding- It is not known whether topiramate passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.
Children- Although there is no specific information comparing the use of topiramate in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.
Older adults- In studies done to date that have included adults older than 60 years of age, topiramate has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking topiramate, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of topiramate. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Take this medicine every day exactly as ordered by your doctor in order to improve your condition as much as possible. Do not take more or less of it, and do not take it more or less often than your doctor ordered.
Topiramate may be taken with or without food, on a full or an empty stomach. Swallow the tablets whole, without breaking, crushing, or chewing them. The bitter taste may be more noticeable if the tablets are held in the mouth or chewed. The capsules may be swallowed whole, or the contents of the capsule may be opened and the contents sprinkled on a small amount (teaspoonful) of soft food (such as applesauce, custard, ice cream, oatmeal, pudding, or yogurt) and swallowed immediately without chewing
The dose of topiramate will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of topiramate. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking topiramate .
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
This medicine may cause some people to have blurred vision, double vision, clumsiness or unsteadiness, or to become dizzy, drowsy, or have trouble in thinking. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well.
Check with your doctor immediately if you experience a decrease in vision, blurred vision, double vision or pain around the eyes.
Oral contraceptives (birth control pills) containing estrogen may not work properly if you take them while you are taking topiramate. Unplanned pregnancies may occur. You should use a different or additional means of birth control while you are using topiramate. If you have any questions about this, check with your doctor or pharmacist.
It is important that you drink plenty of fluids every day during therapy with topiramate to help prevent kidney stones from forming.
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Topiramate may cause a change in your sense of taste.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in the product labeling, topiramate is used in certain patients with the following medical conditions:
Last updated: Tue, 06 Jan 2009 00:20:03 GMT