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Other drug names: A-Am An-Az B C-Ch Ci-Cz D-Dh Di-Dz E F G H I-J K-L M-Mh Mi-Mz N-Nh Ni-Nz O P-Pl Pm-Pz Q-R S-Sn So-Sz T-To Tp-Tz U-V W-Z 0-9   

Pamidronate Injection

About your treatment

Your doctor has ordered pamidronate to help treat your illness. The drug will be added to an intravenous fluid that will drip through a needle or catheter into your vein. You will receive your dose of pamidronate as an infusion that may last several hours or all day.

Pamidronate is used to treat Paget's disease, hypercalcemia (too much calcium in the blood) associated with malignancy, and osteolytic lesions and bone metastases. Pamidronate helps prevent bone breakdown. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor. The length of treatment depends on how you respond to the medication.


Before administering pamidronate,

  • tell your doctor and pharmacist if you are allergic to pamidronate, etidronate (Didronel), alendronate (Fosamax), tiludronate (Skelid), risedronate (Actonel), or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, calcium supplements, and vitamins.
  • tell your doctor if you have or have ever had anemia, gastrointestinal problems, hypocalcemia, kidney disease, leukopenia, or thrombocytopenia.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking pamidronate, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking pamidronate.
  • You should make sure your diet contains enough calcium and vitamins. You should discuss this with your health care provider.

Administering your medication

Before you administer pamidronate, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored or if it contains particles. Use a new solution, but show the damaged one to your health care provider.

It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason. Do not administer it more often or for longer periods than your doctor tells you. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.

Side effects

Although side effects from pamidronate are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

  • loss of appetite
  • upset stomach
  • vomiting
  • fever
  • constipation
  • muscle weakness
  • swelling of ankles
  • dizziness
  • headache
  • bone pain

If you experience any of the following symptoms, call your health care provider immediately:

  • seizures
  • eye pain
  • irregular heartbeat
  • very stiff muscles

Storing your medication

  • Your health care provider will probably give you a several-day supply of pamidronate at a time. You will be told how to prepare each dose.
  • You may be told to store pamidronate in the refrigerator. Take your dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
  • Do not allow pamidronate to freeze.

Store your medication only as directed. Make sure you understand what you need to store your medication properly.Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of the reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Signs of infection

If you are receiving pamidronate in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:

  • tenderness
  • warmth
  • irritation
  • drainage
  • redness
  • swelling
  • pain

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Last updated: Tue, 06 Jan 2009 00:20:03 GMT