Please be patient! It may take up to ONE minute to load all the Engines.
Problems? Please contact our support.
In the U.S.-
Pimozide ( PIM-oh-zide) is used to treat the symptoms of Tourette's syndrome. It is meant only for patients with severe symptoms who cannot take or have not been helped by other medicine.
Pimozide works in the central nervous system to help control the vocal outbursts and uncontrolled, repeated movements of the body (tics) that interfere with normal life. It will not completely cure the tics, but will help to reduce their number and severity.
Pimozide may also be used for other conditions as determined by your doctor.
This medicine is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pimozide, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to pimozide, haloperidol, or other medicines used to treat mental illness. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Diet- It is very important that you do not take pimozide with grapefruit juice. Studies have shown that taking pimozide with grapefruit juice may cause heart rhythm problems.
Pregnancy- Studies in rats and rabbits given more than the highest recommended human dose of pimozide have shown fewer pregnancies, slowed development of the fetus, and toxic effects in the mother and fetus.
Breast-feeding- It is not known whether pimozide passes into breast milk.
Children- Children are especially sensitive to the effects of pimozide. This may increase the chance of side effects during treatment. Pimozide usually is not used in children for any condition other than Tourette's syndrome.
Older adults- Constipation, dizziness or fainting, drowsiness, dryness of mouth, and trembling of the hands and fingers, and symptoms of tardive dyskinesia (such as rapid, worm-like movements of the tongue or any other uncontrolled movements of the mouth, tongue, or jaw, and/or arms and legs) may be especially likely to occur in the elderly, who are usually more sensitive than younger adults to the effects of pimozide.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking pimozide, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of pimozide. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Use pimozide only as directed by your doctor . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
The dose of pimozide will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of pimozide. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using pimozide .
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of pimozide you take may be changed often to meet the needs of your condition and to help avoid unwanted effects.
Do not take azithromycin, clarithromycin, dirithromycin, disopyramide, erythromycin, indinavir, itraconazole, ketoconazole, maprotiline, nefazodone, nelfinavir, phenothiazines, probucol, procainamide, quinidine, ritonavir, saquinavir, tricyclic antidepressants, troleandomycin, or zileuton while you are taking pimozide , or you may develop a very serious irregular heartbeat.
Do not suddenly stop taking this medicine without first checking with your doctor . Your doctor may want you to reduce gradually the amount you are taking before stopping completely. This will allow your body time to adjust and help to avoid worsening of your medical condition.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine .
This medicine may cause some people to become drowsy or less alert or to have blurred vision or muscle stiffness, especially as the amount of medicine is increased. Even if you take pimozide at bedtime, you may feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see well or if you do not have good muscle control .
Although not a problem for many patients, dizziness, lightheadedness, or fainting may occur when you get up from a sitting or lying position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor.
Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine . Taking pimozide together with medicines that are used during surgery or dental or emergency treatment may increase the CNS depressant effects.
Pimozide may cause dryness of the mouth. For temporary relief, use sugarless gum or candy, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.
Side Effects of This Medicine
Along with its needed effects, pimozide can sometimes cause serious unwanted effects. Tardive dyskinesia (a movement disorder) may occur and may not go away after you stop using the medicine. Signs of tardive dyskinesia include fine, worm-like movements of the tongue, or other uncontrolled movements of the mouth, tongue, cheeks, jaw, or arms and legs. Other serious but rare side effects, such as abnormal heart rhythm or the neuroleptic malignant syndrome, may also occur. You and your doctor should discuss the good this medicine will do as well as the risks of taking it .
Stop taking pimozide and get emergency help immediately if any of the following side effects occur:
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
After you stop using pimozide, it may still produce some side effects that need attention. During this period of time, check with your doctor as soon as possible if you notice any of the following side effects:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, pimozide is used in certain patients with the following medical condition:
Other than the above information, there is no additional information relating to proper use, precautions, or side effects for this use.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT