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Mequinol and Tretinoin (Topical)
In the U.S.-
Mequinol and Tretinoin (MEC-kwin-all and TRET-i-noyn ) is used to treat areas of the skin that have become darker after repeated exposure to the sun. These areas are called solar lentigines, or age or liver spots.
Mequinol and tretinoin is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For mequinol and tretinoin, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to acitretin, etretinate, isotretinoin, mequinol, tretinoin, or vitamin A preparations. Also tell your health care professional if you are allergic to any other substances, such as preservatives or dyes.
Pregnancy- Mequinol and tretinoin has not been studied in pregnant women. Topical mequinol and tretinoin is not recommended during pregnancy. Topical mequinol and tretinoin may cause fetal harm. Before using this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding- It is not known whether mequinol and tretinoin passes into the breast milk. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctors.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of this medicine in children with use in other age groups. Mequinol and tretinoin should not be used in children.
Older adults- This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin. When you are using topical mequinol and tretinoin, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of mequinol and tretinoin topical solution. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
It is very important that you use this medicine only as directed . Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.
Do not apply this medicine to windburned or sunburned skin or on open wounds .
Do not use this medicine in or around the eyes or lips, or inside of the nose . Spread the medicine away from these areas when applying. If the medicine accidentally gets on these areas, wash with water at once.
This medicine usually comes with patient directions. Read them carefully before using the medicine.
To use this medicine:
Follow your doctor's orders or the directions on the label . The following information includes usual dose of topical mequinol and tretinoin. If your dose is different, do not change it unless your doctor tells you to do so.
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
You may notice redness, stinging, burning or irritation when you first start using this medicine. It may take up to 6 months before you notice full beneficial effects, even if you use the medicine every day. Check with your health care professional at any time skin irritation becomes severe or if your age spots get darker in color.
Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as mequinol and tretinoin topical solution :
Using these products along with mequinol and tretinoin may cause mild to severe irritation of the skin. Check with your doctor before using other topical medicines.
Avoid overexposing the treated areas to sunlight, wind, or cold weather . The skin will be more prone to sunburn, dryness, or irritation. Do not use a sunlamp .
Regularly use sunscreen or sunblocking lotions with a sun protection factor (SPF) of at least 15. Also, wear protective clothing and hats, and apply creams, lotions, or moisturizers often.
Check with your doctor any time your skin becomes too dry and irritated . Your health care professional can help you choose the right skin products for you to reduce skin dryness and irritation and may include :
Side Effects of This Medicine
In some animal studies, mequinol and tretinoin has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other studies have not shown the same result and more studies need to be done. It is not known if mequinol and tretinoin topical solution causes skin tumors to develop faster in humans.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT