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Lansoprazole (Systemic)

Brand Names

In the U.S.-

  • Prevacid

In Canada-

  • Prevacid

Category

  • Gastric acid pump inhibitor
  • antiulcer agent

Description

Lansoprazole (lan-SOE-pra-zole ) is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus. Sometimes lansoprazole is used in combination with antibiotics to treat ulcers associated with infection caused by the H. pylori bacteria (germ).

Lansoprazole is also used to treat Zollinger-Ellison disease, a condition in which the stomach produces too much acid.

Lansoprazole works by decreasing the amount of acid produced by the stomach.

This medicine is available only with your doctor's prescription.

    Oral
  • Delayed-release capsules (U.S. and Canada)



Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lansoprazole, the following should be considered:

Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to lansoprazole. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy- Studies have not been done in humans. However, studies in animals have not shown that lansoprazole causes harm to the fetus.

Breast-feeding- Lansoprazole may pass into the breast milk. Since this medicine has been shown to cause unwanted effects such as tumors in animals, it may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children- There is no specific information comparing the use of lansoprazole in children with use in other age groups.

Older adults- In studies done to date that have included older adults, lansoprazole did not cause different side effects or problems than it did in younger adults.

Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking lansoprazole, it is especially important that your health care professional know if you are taking any of the following:

  • Sucralfate (e.g., Carafate)-Lansoprazole should be taken at least 30 minutes before sucralfate so that lansoprazole will be properly absorbed



Proper Use of This Medicine

Take lansoprazole before a meal, preferably in the morning .

Swallow the capsule whole. Do not crush, break, or chew the capsule . If you cannot swallow the capsule whole, you may open it and sprinkle the granules contained in the capsule on one tablespoonful of applesauce and swallow it immediately; or you may mix the granules in some fruit or vegetable juice and drink it immediately. Juices you may use include apple, cranberry, grape, orange, pineapple, prune, tomato, and V-8 vegetable juice. Do not chew or crush the granules .

Take this medicine for the full time of treatment, even if you begin to feel better . Also, keep your appointments with your doctor for check-ups so that your doctor will be better able to tell you when to stop taking this medicine.

Dosing-

The dose of lansoprazole will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of lansoprazole. If your dose is different, do not change it unless your doctor tells you to do so.

The number of doses you take each day and the length of time you take the medicine depend on the medical problem for which you are taking lansoprazole .

  • For oral dosage form (delayed-release capsule):
    • To treat gastroesophageal reflux disease (GERD):
      • Adults-15 to 30 mg once a day, preferably taken in the morning before a meal.
      • Children up to 18 years of age-Use and dose must be determined by your doctor.
    • To treat duodenal ulcers:
      • Adults-At first, 15 milligrams (mg) once a day, preferably taken in the morning before a meal. Your doctor may increase your dose if needed.
      • Children up to 18 years of age-Use and dose must be determined by your doctor.
    • To treat duodenal ulcers related to infection with H. pylori:
      • Adults-30 mg plus amoxicillin 1000 mg (1 gram) plus clarithromycin 500 mg, taken together before meals twice a day for ten to fourteen days. Alternatively, your doctor may want you to take lansoprazole 30 mg plus amoxicillin 1000 mg (1 gram) before meals three times a day for fourteen days.
      • Children up to 18 years of age-Use and dose must be determined by your doctor.
    • To treat gastric ulcers:
      • Adults-15 to 30 mg once a day, preferably taken in the morning before a meal.
      • Children up to 18 years of age-Use and dose must be determined by your doctor.
    • To treat conditions in which the stomach produces too much acid:
      • Adults-At first, 60 mg once a day, preferably taken in the morning before a meal. Your doctor may increase your dose if needed.
      • Children up to 18 years of age-Use and dose must be determined by your doctor.

Missed dose-

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage-

To store this medicine:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.


Precautions While Using This Medicine

It is important that your doctor check your progress at regular intervals . If your condition does not improve, or if it becomes worse, discuss this with your doctor.


Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • More common
    • Diarrhea;  skin rash or itching 

  • Less common
    • Abdominal or stomach pain;  increased or decreased appetite;  joint pain;  nausea;  vomiting 

  • Rare
    • Anxiety;  cold or flu-like symptoms;  constipation;  increased cough;  mental depression;  muscle pain;  rectal bleeding;  unusual bleeding or bruising 

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

  • More common
    • Dizziness;  headache 

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.



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Last updated: Tue, 06 Jan 2009 00:20:03 GMT
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