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Glutethimide (gloo-TETH-i-mide) is used to treat insomnia (trouble in sleeping). However, it has generally been replaced by safer and more effective medicines for the treatment of insomnia. If glutethimide is used regularly (for example, every day) to help produce sleep, it is usually not effective for more than 7 days.
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For glutethimide the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to glutethimide. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Studies of effects in pregnancy have not been done in either humans or animals. However, too much use of glutethimide during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth.
Breast-feeding- Glutethimide passes into the breast milk and may cause drowsiness in nursing babies.
Children- Studies on this medicine have been done only in adult patients and there is no specific information comparing use of glutethimide in children with use in other age groups.
Older adults- Elderly people may be especially sensitive to the effects of glutethimide. This may increase the chance of side effects during treatment.
Other medicines- Although certain medicines should not be used together at all, in other cases 2 different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking glutethimide it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of glutethimide. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming.
The dose of glutethimide will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of glutethimide. If your dose is different, do not change it unless your doctor tells you to do so.
To store this medicine:
Precautions While Using This Medicine
If you will be taking this medicine regularly for a long time:
This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine .
Before you have any medical tests, tell the doctor in charge that you are taking this medicine. The results of the metyrapone test may be affected by this medicine.
If you think you or someone else may have taken an overdose of this medicine, get emergency help at once . Taking an overdose of glutethimide or taking alcohol or other CNS depressants with glutethimide may lead to unconsciousness and possibly death. Some signs of an overdose are continuing confusion, severe weakness, shortness of breath or slow or troubled breathing, convulsions (seizures), slurred speech, staggering, and slow heartbeat.
This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert .
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor if you notice any of the following side effects:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT