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Furazolidone (fyoor-a-ZOE-li-done ) is used to treat bacterial and protozoal (proe-toe-ZOE-al) infections. It works by killing bacteria and protozoa (tiny, one-celled animals). Some protozoa are parasites that can cause many different kinds of infections in the body.
Furazolidone is taken by mouth. It works inside the intestinal tract to treat cholera, colitis, and/or diarrhea caused by bacteria, and giardiasis (jee-ar-DYE-a-siss) . This medicine is sometimes given with other medicines for bacterial infections.
Furazolidone may cause some serious side effects when taken with certain foods, beverages, or other medicines . Check with your health care professional for a list of products that should be avoided.
Furazolidone is available only with your doctor's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For furazolidone, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to furazolidone or to any related medicines such as nitrofurantoin (e.g., Furadantin) or nitrofurazone (e.g., Furacin). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Studies have not been done in humans. However, furazolidone has not been shown to cause birth defects or other problems in humans or in animals given high doses for a long time.
Breast-feeding- It is not known whether furazolidone passes into breast milk. However, breast-feeding is not recommended for nursing babies up to 1 month of age because furazolidone may cause anemia.
Children- Because furazolidone may cause anemia, use in infants up to 1 month of age is not recommended.
Older adults- Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of furazolidone in the elderly with use in other age groups.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking furazolidone, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of furazolidone. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Do not give furazolidone to infants up to 1 month of age , unless otherwise directed by your doctor. This medicine may cause anemia in these patients.
Furazolidone may be taken with food to lessen the chance of an upset stomach.
To use the oral suspension :
To help clear up your infection completely, keep taking furazolidone for the full time of treatment , even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return. Do not miss any doses .
The dose of furazolidone will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of furazolidone. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets or teaspoonfuls of suspension that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking furazolidone .
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
It is important that your doctor check your progress at regular visits. This is to check whether or not the infection is cleared up completely.
If your symptoms do not improve within a week, or if they become worse, check with your doctor.
Drinking alcoholic beverages or taking other alcohol-containing preparations (for example, elixirs, cough syrups, tonics, or injections of alcohol) while taking furazolidone may rarely cause problems. These problems include increased side effects such as redness of the face, difficult breathing, fainting, and a feeling of tightness in the chest. These side effects usually go away within 24 hours without treatment. However, these effects may occur if you drink alcoholic beverages for up to 4 days after you stop taking furazolidone. Therefore, you should not drink alcoholic beverages or take other alcohol-containing preparations while you are taking furazolidone and for 4 days after stopping it .
Certain foods, drinks, or other medicines may cause very dangerous reactions, such as severe high blood pressure, when taken with furazolidone. Aged or fermented foods and drinks commonly contain tyramine or other substances that increase blood pressure. To avoid such reactions, the following measures are recommended:
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
This medicine commonly causes dark yellow to brown discoloration of urine. This side effect does not usually need medical attention.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT