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Follitropin Beta (Systemic)
In the U.S.-
Follitropin beta (fol-li-TROE-pin BAY-ta) is a hormone identical to follicle-stimulating hormone (FSH) produced by the pituitary gland. FSH helps to develop eggs in the ovaries.
Follitropin beta is used as a fertility medicine to develop eggs in women who have not been able to become pregnant because of problems in ovulation. Also, many women wanting to become pregnant will use this medicine while enrolled in a fertility program that uses procedures such as in vitro fertilization (IVF) or embryo transfer (ET). Follitropin beta may be used with other medicines for these purposes.
Some patients may be treated with another hormone called gonadotropin-releasing hormone agonist (GnRHa) before starting treatment with follitropin beta. GnRHa reduces the amount of FSH released from the pituitary gland. This is done so that the doctor can replace their FSH by using follitropin beta in the proper amounts each day to achieve fertility.
Follitropin beta is available only with your doctor's prescription, in the following dosage form(s):
Before Using This Medicine
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For follitropin beta, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual reaction to follitropin beta or similar medicines. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Follitropin beta is not needed or recommended for use during pregnancy. Since women using follitropin beta may be more likely to have more than one child at a time, the problems of multiple births may be increased for women using this medicine. Also, this medicine has been shown to overstimulate the ovaries (ovarian hyperstimulation syndrome [OHSS]) for a longer time in some women who become pregnant than in women developing this syndrome who do not become pregnant. Signs of this syndrome include severe abdominal pain, nausea, rapid weight gain, and vomiting. Before using this medicine, make sure your doctor knows if you are pregnant.
Breast-feeding- It is not known whether follitropin beta passes into the breast milk. However, this medicine has not been reported to cause problems in nursing babies.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your doctor and pharmacist if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other medical problems- The presence of other medical problems may affect the use of follitropin beta. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
To make using follitropin beta as safe and reliable as possible, you should understand how and when to use this medicine and what effects may be expected. A paper with information for the patient will be given to you with your filled prescription, and will provide many details concerning the use of follitropin beta. Read this paper carefully and ask your health care professional for any additional information or explanation.
Sometimes follitropin beta can be given by injection at home. If you are using this medicine at home:
Tell your doctor when you use your last dose of follitropin beta . Follitropin beta often requires that another hormone called human chorionic gonadotropin (hCG) be given as a single dose the day after the last dose of follitropin beta is given. Your doctor will give you this medicine or arrange for you to get this medicine at the right time.
The dose of follitropin beta will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of follitropin beta. If your dose is different, do not change it unless your doctor tells you to do so.
If you miss a dose of this medicine, discuss with your doctor when you should receive your next dose. Do not double doses. If you have any questions about this, check with your doctor.
To store this medicine:
Precautions While Using This Medicine
It is very important that your doctor check your progress often at regular visits, such as every other day , to make sure that the medicine is working properly and to check for unwanted effects. Your doctor will probably want to follow the developing eggs inside the ovaries by doing an ultrasound examination and measuring hormones in your blood stream. After you no longer receive follitropin beta, your progress still must be checked every other day for at least 2 weeks .
If your doctor has asked you to record your basal body temperature (BBT) daily, make sure that you do this every day. Using a BBT record or some other method, your doctor will help you decide when you are most fertile and when ovulation occurs. It is important that sexual intercourse take place around the time when you are most fertile to give you the best chance of becoming pregnant. Follow your doctor's directions carefully .
If abdominal pain occurs with use of follitropin beta, discontinue treatment and report the problem to your doctor immediately. Do not receive the injection of hCG and avoid sexual intercourse .
This medicine may cause some people to become dizzy. If this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert while you are using follitropin beta and for 24 hours after you stop using it.
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
There is a rare chance that serious lung and blood problems can occur with use of follitropin beta. Discuss these possible effects with your doctor.
Stop taking this medicine and get emergency help immediately if any of the following side effects occur:
Check with your doctor as soon as possible if any of the following side effects occur:
The following side effects have not been reported for follitropin beta, but may occur because they have been reported for similar medicines . Some of these side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor immediately if you notice any of the following side effects:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT