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In the U.S.-
Fulvestrant ( Fool-VES-trant) is a medicine that is used to treat breast cancer.
Many breast cancer tumors grow in response to estrogen. This medicine blocks the effects of the estrogen hormone in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor.
This medicine is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fulvestrant the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to fulvestrant. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Tell your doctor if you are pregnant or if you intend to become pregnant. Fulvestrant has not been studied in pregnant women. However, studies in animals have shown that fulvestrant causes serious problems with the fetus. Be sure that you have discussed this with your doctor before taking this medicine. It is best to avoid pregnancy during treatment with this medicine.
Tell your doctor right away if you think you have become pregnant while taking fulvestrant
Breast-feeding- It is not known whether fulvestrant passes into the breast milk. However, because this medicine may cause serious side effects, breast-feeding generally is not recommended while you are taking it.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of fulvestrant in children with use in other age groups.
Older adults- Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. When you are taking fulvestrant, it is especially important that your doctor and pharmacist know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of fulvestrant. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Fulvestrant is usually given by a health care professional. However, medicines given by injection are sometimes used at home. If you will be using fulvestrant at home, your health care professional will teach you how the injections are to be given. You will also have a chance to practice giving them. Be certain that you understand exactly how the medicine is to be injected. Do not reuse needles and syringes.
Put used needles and syringes in a puncture-resistant disposable container, or dispose of them as directed by your health care professional.
The dose of fulvestrant will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of fulvestrant.
If you miss a dose of this medicine, take it as soon as possible. Do not double doses or use more often than one dose every 30 days. If you have any questions about this, check with your doctor.
To store this medicine:
Precautions While Using This Medicine
Your doctor will want to check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.
For women of childbearing age-It is very important that you do not become pregnant while taking fulvestrant.
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT