Please be patient! It may take up to ONE minute to load all the Engines.
Problems? Please contact our support.
In the U.S.-
Another commonly used name is VP-16.
Etoposide ( e-toe-POE-side) belongs to the group of medicines known as antineoplastic agents. It is used to treat cancer of the testicles and certain types of lung cancer. It is also sometimes used to treat some other kinds of cancer in both males and females.
The exact way that etoposide acts against cancer is not known. However, it seems to interfere with the growth of the cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by etoposide, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.
Before you begin treatment with etoposide, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
This medicine is available only with your doctor's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For etoposide, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to etoposide.
Pregnancy- There is a good chance that this medicine will cause birth defects if it is being used at the time of conception or during pregnancy. In addition, many cancer medicines may cause sterility, which could be permanent. Although sterility has not been reported with etoposide, the possibility should be kept in mind.
Be sure that you have discussed this with your doctor before receiving this medicine. Before taking etoposide make sure your doctor knows if you are pregnant or if you may become pregnant. It is best to use some kind of birth control while you are taking etoposide. Tell your doctor right away if you think you have become pregnant while taking etoposide.
Breast-feeding- Because etoposide may cause serious side effects, breast-feeding is generally not recommended while you are receiving it.
Children- Although this medicine has been used in children, there is no specific information comparing use of etoposide in children with use in other age groups. However, children who receive high doses may be more likely to have a serious allergic reaction to this medicine.
Older adults- Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of etoposide in the elderly with use in other age groups.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking or receiving etoposide, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of etoposide. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Take etoposide only as directed by your doctor . Do not use more or less of it, and do not use it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.
Etoposide is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the proper time and do not mix them. If you are taking some of these medicines by mouth, ask your health care professional to help you plan a way to remember to take your medicines at the right times.
Etoposide often causes nausea, vomiting, and loss of appetite, which may be severe. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Ask your health care professional for ways to lessen these effects.
If you vomit shortly after taking a dose of etoposide, check with your doctor. You will be told whether to take the dose again or to wait until the next dose.
The dose of etoposide will be different for different patients. The dose that is used may depend on a number of things, including what the medicine is being used for, the patient's size, whether the medicine is being given by mouth or by injection, and whether or not other medicines are also being taken. If you are taking or receiving etoposide at home, follow your doctor's orders or the directions on the label . If you have any questions about the proper dose of etoposide, ask your doctor.
If you miss a dose of this medicine, do not take the missed dose at all and do not double the next one. Instead, go back to your regular dosing schedule and check with your doctor.
To store this medicine:
Precautions While Using This Medicine
It is very important that your doctor check your progress at regular visits to make sure that etoposide is working properly and to check for unwanted effects.
While you are being treated with etoposide, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval . Etoposide may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have taken oral polio vaccine within the last several months. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.
Etoposide can temporarily lower the number of white blood cells in your blood, increasing the chance of your getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.
Check with your doctor or nurse immediately if any of the following side effects occur:
Check with your health care professional as soon as possible if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
This medicine often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor or nurse.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, etoposide is used in certain patients with the following medical conditions:
Other than the above information, there is no additional information relating to proper use, precautions, or side effects for these uses.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT