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In the U.S.-
Eplerenone ( ep-LAYR-eh-nown) belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).
High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Hypertension may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
This medicine is available only with your healthcare professional's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your healthcare professional will make. For eplerenone the following should be considered:
Allergies- Tell your healthcare professional if you have ever had any unusual or allergic reaction to eplerenone. Also tell your healthcare professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- eplerenone has not been studied in pregnant women. Before taking this medicine, make sure that your healthcare professional knows if you are pregnant or if you may become pregnant.
Breast-feeding- It is not known whether eplerenone passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their healthcare professional.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of eplerenone in children with use in other age groups.
Older adults- Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Although eplerenone has been given to a limited number of elderly people and has not been shown to cause different side effects in the elderly than in other age groups. Some elderly people may have a greater sensitivity to certain medicines.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your healthcare professional may want to change the dose, or other precautions may be necessary. When you are taking eplerenone, it is especially important that your healthcare professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of eplerenone. Make sure you tell your healthcare professional if you have any other medical problems, especially:
Proper Use of This Medicine
The dose of eplerenone will be different for different patients. Follow your healthcare professional's orders or the directions on the label . The following information includes only the average doses of eplerenone. If your dose is different, do not change it unless your healthcare professional tells you to do so.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
It is very important that your healthcare professional check your progress at regular visits. This will allow your healthcare professional to see if the medicine is working properly and to decide if you should continue to take it.
Do not take other medicines unless they have been discussed with your healthcare professional. This especially includes potassium supplements or salt substitutes containing potassium. Check with your healthcare professional before taking amiloride, spironolactone, triamterene, ketoconazole, or itraconazole.
Side Effects of This Medicine
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your healthcare professional immediately if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your healthcare professional if any of the following side effects continue or are bothersome.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT