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Piperazine (PI-per-a-zeen) belongs to the family of medicines called anthelmintics ( ant-hel-MIN-tiks) . Anthelmintics are used in the treatment of worm infections.
Piperazine is used to treat:
Piperazine works by paralyzing the worms. They are then passed in the stool.
Piperazine is available only with your doctor's prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For piperazine, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to piperazine or ethylenediamine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy- Piperazine has not been studied in pregnant women. Piperazine has not been shown to cause birth defects or other problems in animal studies. However, piperazine, taken by mouth, may be changed within the body into a substance that may cause cancer. Before taking piperazine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding- It is not known whether piperazine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.
Children- Children may be especially sensitive to the effects of piperazine. This may increase the chance of side effects during treatment.
Older adults- Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of piperazine in the elderly with use in other age groups.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking piperazine, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of piperazine. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
No special preparations or other steps (for example, special diet, fasting, other medicines, laxatives, or enemas) are necessary before, during, or immediately after you take piperazine.
Piperazine may be taken with or without food or on a full or empty stomach. However, if your doctor tells you to take the medicine a certain way, take it exactly as directed.
For patients taking the granules for oral solution form of piperazine:
Take this medicine only as directed . Do not take more of it and do not take it more often than your doctor ordered. To do so may increase the chance of serious side effects.
To help clear up your infection completely, take this medicine in regularly spaced doses as ordered by your doctor . In some infections, a second treatment with this medicine may be required to clear up the infection completely. Do not miss any doses .
For patients taking piperazine for pinworms :
The dose of piperazine will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of piperazine. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets or teaspoonfuls of solution or suspension of the medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking piperazine .
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
It is important that your doctor check your progress after treatment. This is to make sure that the infection is cleared up completely, and to allow your doctor to check for any unwanted effects.
If your symptoms do not improve after you have taken this medicine for the full course of treatment, or if they become worse, check with your doctor.
For patients taking piperazine for pinworms :
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT