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In the U.S.-
Enoxaparin ( e-nox-a-PA-rin) is used to prevent deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. This medicine is used for several days after hip or knee replacement surgery, and in some cases following abdominal surgery, while you are unable to walk. It is during this time that blood clots are most likely to form. Enoxaparin is also used if you are unable to get out of bed because of a serious illness. In addition, enoxaparin is used to prevent blood clots from forming in the arteries of the heart during certain types of chest pain and heart attacks. Enoxaparin also may be used for other conditions as determined by your doctor.
Enoxaparin is available only with your doctor's prescription, in the following dosage form:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For enoxaparin, the following should be considered:
Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to enoxaparin or to heparin. Also tell your health care professional if you are allergic to any other substances, such as foods, especially pork or pork products, preservatives, or dyes.
Pregnancy- Enoxaparin has not had adequate studies performed in pregnant women. However, if you are pregnant your doctor will need to closely monitor you because of an increased risk of bleeding. In pregnant women who have an artificial heart valve, enoxaparin is not recommended.
Breast-feeding- It is not known whether this medicine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctor.
Children- Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of enoxaparin in children with use in other age groups.
Older adults- This medicine has been tested and has been shown to cause an increased risk of side effects or problems in older people than it does in younger adults. You doctor may adjust your dose, especially if you are less than 45 kg (99 lbs.) of body weight or in elderly patients with decreased kidney function.
Other medicines- Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are using enoxaparin, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems- The presence of other medical problems may affect the use of enoxaparin. Make sure you tell your doctor if you have any other medical problems, especially:
Also, tell your doctor if you have received enoxaparin or heparin before and had a reaction to either of them called thrombocytopenia, or if new blood clots formed while you were receiving the medicine.
In addition, tell your doctor if you have recently given birth, fallen or suffered a blow to the body or head, or had medical or dental surgery . These events may increase the risk of serious bleeding when you are taking enoxaparin.
Proper Use of This Medicine
If you are using enoxaparin at home, your health care professional will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your health care professional if you have any problems using the medicine .
Put used syringes in a puncture-resistant, disposable container , or dispose of them as directed by your health care professional.
The dose of enoxaparin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of enoxaparin. If your dose is different, do not change it unless your doctor tells you to do so.
If you miss a dose of this medicine, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
To store this medicine:
Precautions While Using This Medicine
Tell all your medical doctors and dentists that you are using this medicine .
Check with your doctor immediately if you notice any of the following side effects:
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Stop using this medicine and check with your doctor immediately if any of the following side effects occur:
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Last updated: Tue, 06 Jan 2009 00:20:03 GMT